Operational Excellence Manager

About myTomorrows 

myTomorrows is a global health tech company dedicated to breaking down barriers for patients seeking treatment options.   

We strive to enable earlier and better treatment access by bridging the gap between those searching for possible options, and the companies who develop them. We work closely with patients, healthcare professionals, trial sites, patient advocacy groups, and BioPharma – connecting key stakeholders in the drug development ecosystem.   

We’ve developed a cutting-edge AI-powered technology platform that simplifies and streamlines access to drugs in development. To support our users and clients, we have a range of industry-expert specialized teams ready to help. Our services include clinical trial patient recruitment, Expanded Access Program management and Real-World Data collection.   

With a global footprint spanning 134 countries, to date we’ve supported over 17,000 patients, 3,000 physicians and 350 sites, earning the trust of 60+ BioPharma companies. In October 2025, we closed a €25M investment with Avego Healthcare Capital to fuel our global ambitions and scale the business.  

Join us in shaping the future of treatment access - making tomorrow’s therapies accessible for people who need them today. 

The Opportunity: Operational Excellence Manager

The Operational Excellence Manager Improves operational processes to enhance efficiency, effectiveness, scalability and quality across myTomorrows. The role identifies, analyzes, and optimizes business processes using data-driven insights to achieve sustainable improvements, ensuring processes align with organizational objectives and supporting a culture of continuous improvement. This role will report to the Director, Operational Excellence (Diane says hi!).

You'll be joining a small Operational Excellence function with a portfolio of active initiatives already in flight. The function has foundations in place, but there is meaningful room to shape how things are done; this is not a role where you inherit a fully-defined playbook and execute against it. If you're energized by a mix of picking up existing work and putting your own stamp on it, this is a strong fit.

This role is hands-on and cross-functional. Success requires strong stakeholder management, excellent documentation discipline, and the ability to implement change effectively in an environment where teams are busy. The role also serves as a key interface between Operations and Product Development to ensure operational processes are effectively enabled by systems and tooling, including AI and automation capabilities.

Note: This role is hybrid out of our Amsterdam office, we will only consider candidates who live within commuting distance to our office in Amsterdam for this position.

Key Responsibilities

• Lead operational excellence initiatives: Identify inefficiencies, run root-cause analysis, and deliver scalable process improvements with measurable outcomes (end-to-end: definition → design → implementation → adoption → tracking).

• Project oversight: Manage scope, plans, dependencies, risks, and stakeholder actions across multiple initiatives to ensure high-quality delivery and on-time implementation.

• Ops ↔ Product interface (systems enablement): Translate operational needs into clear requirements, support implementation of system/process changes, and ensure solutions work in real operational workflows.

• AI & automation integration: Identify where AI tools and automation can meaningfully reduce manual effort, improve consistency, or accelerate throughput.

• Collaborate with the AI/Automation workstream to scope, test, and embed solutions into operational processes — maintaining appropriate human oversight, especially in regulated contexts.

• Evaluate AI output quality as part of process design, not as an afterthought.

• Lead GxP / CSV related implementations: Partner with Quality and Product to support and/or lead Computer System Validation (CSV) for GxP-touching systems, ensuring appropriate documentation, test evidence, traceability, training alignment, and change control as applicable.

• Stakeholder & change management: Influence without authority, align priorities, and drive adoption through practical rollouts that respect operational workload constraints and provide enablement.

• Documentation excellence: Create and support maintaining high-quality process documentation (process maps, SOPs/work instructions, templates, decision logs).

• Establish standards and ways of working so teams can document consistently, accurately and keep it current, including how AI-generated content is reviewed, versioned, and approved.

• Training & embedment: Develop training materials and deliver/coordinate training to ensure process changes are adopted and sustained including support to the AI enablement team to help build capability in the team’s use of AI tools where relevant.

• Data & KPI management: Define KPIs upfront per initiative; measure, track, analyze trends, and report impact using data analytics tools.

Requirements

• Experience: 4–6 years in Operational Excellence / Process Improvement / Operations, with demonstrated success leading cross-functional improvement initiatives.

• Proven experience operating in validated environments and executing/participating in CSV activities for GxP-touching systems.

• Comfortable working with AI tools in a professional context, not necessarily as a builder, but as a critical and informed user.

• Strong capability in process analysis, continuous improvement methods, and data-driven decision making.

• Experience with project/process management tools; Smartsheet a plus.

• Excellent communication and stakeholder management skills; ability to drive change in fast-paced operational settings.

• Comfortable operating in a maturing function where frameworks are being built, not just inherited.

• Strong writing skills and a high bar for documentation quality; ability to coach and enable others to follow the same standards.

• Highly preferred: work experience in life sciences (e.g., drug development, expanded access programs, clinical trial recruitment) and/or highly regulated environments.

Equal opportunities

myTomorrows is an Equal Opportunity Employer and, beyond upholding discrimination-free practices, we are committed to cultivating a workplace where difference and diversity are protected and celebrated. The best work comes from our best selves, and we go to great lengths in supporting our team members to be just that.